Perfecting the Genetic Code with an RNP Complex

An increasingly complex code.

Protein evolution with an expanded genetic code.

We have devised a phage display system in which an expanded genetic code is available for directed evolution. This system allows selection to yield proteins containing unnatural amino acids should such sequences functionally outperform ones containing only the 20 canonical amino acids. We have optimized this system for use with several unnatural amino acids and provide a demonstration of its ut...

Perfecting Kant's highest good

Perfecting Pregnancy via Preimplantation Genetic Screening: The Quest for an Elusive Standard of Care

Introduction ................................................................................................................... 1295 I. Assessing the Clinical Benefits of Optimized PGS-Aneuploidy Screening Techniques ........................................................................................................ 1298 II. Contemporary Legal Doctrines Governing a Physician’s Standard of ...

An Alternative Cracking of The Genetic Code

We propose 22 ‘unique’ solutions to the Genetic code: an alternative cracking, from the perspective of a Mathematician. INTRODUCTION The Genetic code is now known to consist of triplet bases specifying for an amino acid (1). But before any biochemical appreciation of the genetic code, a page copy of DNA of any kind ordinarily looks like a cryptographic code – a discrete set of symbols produced ...